HTH 245 Chapter Notes - Chapter 12: Lymphadenopathy, Adaptive Immune System, Cell-Mediated Immunity
Document Summary
Functions to recognize and destroy/eliminate foreign antigens. Nonspecific/innate (inherent, present before infection: skin, cilia, stomach acidity, lysozymes, interferon, complement. Specific/adaptive (develops in response to infection: humoral (antibody) immunity, cell-mediated immunity. Varies within the individual and between individuals. Mechanical and chemical barriers: skin: is the first line of defense against microbial infection it is a physical barrier that blocks the entry of microbes. Blood: cellular and protein components in blood contribute to innate (nonspecific) immunity, adaptive (specific), or both, white blood cells (leukocytes): Basophils: rich in granules of histamine, allergic response. Eosinophils: eosinophilia seen in worm infections, allergies. Lymphocytes: are the crucial cells of adaptive response: t lymphocytes: t- helper and cytotoxic cells, b lymphocytes: producers of antibodies, protein components (active in immunity) Antibodies: or immunoglobulins, found in gamma globulin. They recognize and bind to specific foreign antigens (adaptive response) Can bring about lysis (destruction by chemical attack) of cells. Group of proteins that act to interfere with viral replication.
