Sex differentiation: sex differentiation controlled by hormones, 1st 2 weeks: embryo sexually indifferent, wolffian ducts (precursor to male tract, mullerian ducts (precursor to female tract) If testes present (due to sry) testes secrete: testosterone, mullerian-inhibiting substance (mis) Ovaries: disorders of sexual development, testicular feminization, androgen insensitivity syndrome (ais, xy with external female genitalia, at puberty testosterone is converted to estrogen fro secondary sex characteristics. Inability to reproduce: puberty (starts at 10-14 years, later in boys, reproductive organs mature (can produce sperm, secondary sexual characteristics develop, leptin increases: 40% higher in females (fat accumulation) Sexual maturation: late teens: reach final height, female reproductive system cycles, female lost ability to reproduce around 45-50. Scrotum: suspended beneath penis, houses testes, allows a cooler environment for sperm development. Figure 22. 6: reproductive tract, vas deferens --> seminal vesicles --> ejaculatory duct --> prostate gland --> urethra --> bulbourethral glands --> ejaculation, accessory glands, seminal vesicles. Secrete alkaline fluid with fructose, enzymes and prostaglandins: table 22. 2.