MC 2000 Chapter : 11Radio
Document Summary
Oscar miller, at univ. of va first to visualize actively transcribing genes in 1969. Miller"s christmas trees rrna transcription: xenopus oocyte. It is arguably one of the best known biological images produced in the last 40 years, amply demonstrating that a picture is worth a thousand words. " joe gall, 2001. The central dogma played out in the eukaryotic cell. Permanent covalent bond: dna can bend when proteins bind; helix is perturbed (opened up), tata box binding protein- (thymine-adenine-thymine-adenine) transcription of most eukaryotic genes requires binding of this protein. (fig 4-5) Dna: dna sequencing revealed that most of the genome of higher eukaryotes does not encode mrnas or any other rnas. Appear to serve no purpose whatsoever in the life cycle of an organism: accounts for ~95% of human chromosomal dna, these non-coding regions are similar in humans, but not identical.
