01:694:301 Chapter Notes - Chapter 15: Myoglobin, Porphyrin, Glycogen Phosphorylase

• School: Rutgers University
• Department: Molecular Biology and Biochemistry
• Course: 01:694:301
• Professor: F.Deis

Document Summary

High energy (cid:8869) of phosphotransfer potential is there large sg why (favorable) Atp hydro l y s l s: resonance stabilization is. Favorable 8 (cid:8869) lowers sg more stable ( e run freely (cid:8869) not confined over molecule) in 1 place: loss of charge - charge repulsion. Atp to adp (cid:8869) reliefs electrostatic repulsion btwn neg p groups: tautomer iz a ti o n isomerize"s into more stable form (ketone) stabilized by : loss of p. Tautomerizes ketone ( mtfable: better solvation of products than reactants, greater # particles greater entropy. Regulation + functionality of to regulate activity want. That in f l u e n c e activity. S u b s t r a t e t. C o fa c t or availability: availability of substrates + cofactor determines enzymatic rxh rate. S y n t h e s l s and de g r a da t t o n.