BCM 475 Chapter Notes - Chapter 20: Glycolysis, Ribose, Pentose
Document Summary
Mode 1 | ribose 5-phosphate is needed more than nadph. 5 glucose 6-phosphate + atp 6 ribose 5-phosphate + adp + 2h+ Dividing cells need ribose 5-phosphate for synthesis of dna precursors. Glycolytic pathway: glucose 6-phosphate fructose 6-phosphate fructose 1,6-biphosphate dhap + Gap: atp is used by the phosphofructokinase needed to convert fructose 6-phosphate. Pp pathway: using the glycolytic pathway"s products: (cid:1005) gap + (cid:1006) fructose 6-phosphate 3 ribose 5- phosphate. Mode 2 | nadph and ribose 5-phosphate are balanced. Glucose 6-phoshate + 2nadp+ + h2o ribose 5-phosphate + 2nadph + 2h+ + co2. Mode 3 | much more nadph is needed than ribose 5-phosphate. Glucose 6-phoshate + 12nadp+ + 7h2o + 12h+ + p + 6co2 + 12nadph. Adipose tissue requires high levels of nadph for fatty acid synthesis. Mode 4 | both nadph and atp are required. Ribose 5-phosphate can be converted into pyruvate: pyruvate can make more atp or be used as a building block.
