MIC 301 Chapter 12: MIC 301 CHAPTERS 12, 20-23 Study Guide

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Chapter 20: pathogenic gram-negative bacteria cocci and bacilli. Constitute largest group of human bacterial pathogens. Have an outer membrane (om) with outer membrane proteins and lipid a making. Lipid a (endotoxin) triggers fever, vasodilation, inflammation, shock, dic. A family of bacteria that primarily reside as normal flora on mucosal surfaces. Neisseria is the only gram negative cocci genus that causes disease. Two species pathogenic to humans: neisseria. gonorrhoeae and neisseria meningitidis. Have antigens on their cell walls that are unique: lipooligosaccharides (los)- composed. Only n. meningitidis produce a capsule of lipid a (endotoxin) and sugar molecules. Fastidious (require blood agar or selective thayer-martin medium) Pathogenic strains can ferment maltose, sucrose, or lactose. Two pathogenic species: neisseria gonorrhoeae- causes gonorrhea, neisseria meningitidis- causes a type of meningitis. Most cases occur in adolescents that are sexually active. More common amongst females (50% vs. 20% chance of infection if encountered an infected other)

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