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PSY 351 (8)
Chapter 4

Study Guide: Chapter 4.docx

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PSY 351
Scott Wersinger

Chapter 4: Psychopharmacology Route of administration Advantage Disadvantage Injection The effect is fast as it goes Once injected, the effect straight into the blood vessel cannot be reversed. Oral Slow effect Intracranial - By pass blood-brain - Risk of infection barrier Intracerebroventricular - Can cause brain damage (I.C.V) - Fast 2) Increase the number of impulse Release of NT with or without impulse Block reuptake or inhibit receptor. Prevent vesicles from releasing NT 3) Neurotransmitter is a chemical that transmit signals from one neuron to another across the synapse 4) Neuromodulator is a substance that alter nerve impulse 5) Control muscle movement a. IonotropicACh receptor & MetabotropicACh receptor b. 6) Monoamines are neurotransmitter that contain one amino group a. Catecholamines is a class of amines that includes dopamine, norepinephrine and epinephrine b. Indoleamines is a class of amines that include 5-HT (serotonin) 7) DAis dopamine 8) Nigrostriatal, Mesolimbic and Mesocortical 9) Tyrosine  DOPA  Hydroxylase  decarboxylase (TH) 13) NMDA=A specialized ionotropic glutamate receptor that controls the calcium channel AMPA = A specialized ionotropic glutamate receptor that controls the sodium channel 14) GABA =Aionotropic receptor that controls the chloride channel Receptor Function Location Acetylcholine - Control muscles and regulate memory. - In most instances, acetylcholine is excitatory. Dopamine - Produces feelings of pleasure when released by the brain
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