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Chapter 27

ANSC 101 Chapter Notes - Chapter 27: Chapter 27, Macrophage, Antigen


Department
Animal Science
Course Code
ANSC 101
Professor
Dr.Moyes
Chapter
27

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ANSC Chapter 27: Immune System
Immunity
- System that allows for the identification of a foreign particle and the subsequent
destruction or metabolism of that particle
- Ability to resist infections or toxins
- Is NOT absolute, immunity exists in varying degrees
The immune system
- Leukocyte: White blood cells, cells of the immune system
- Form 1: Innate
-Non-specific
-Neutrophils and macrophages
- Form 2: Adaptive
-Specific
-Vaccine development
-Lymphocytes
Innate Immunity
- Genetically determined, present at birth
- Neutrophils and macrophages
- Examples: skin, secretions that coat the respiratory and intestinal tracts, chemical make-
up of body components such as acid content of stomach
Adaptive Immunity
- Memory
- Occurs after encountering foreign substances
- Made up of antibodies/antigens
- Vaccines work within this form of immunity
Forms of Adaptive Immunity
- Humoral (B cell lymphocytes; antibodies_
-Antibodies produced in response to antigens- antigen specific response
- Cell-mediated
-Effective against viruses or bacteria that replicate within cells after crossing cell
membranes
Adaptive Immune System Development Occurs in Two Phases
- Passive- newborns depend on antibodies in the colostrum until their own immune
system is functional
- Active individual develops its own specific antibodies against invasive antigens
Vaccines are used in two ways
- Stimulate passive immunity by stimulating antibody production in the colostrum
produced by the dam
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