MIEH 300 Chapter Notes - Chapter 4: Toxic Substances Control Act Of 1976, Organochloride, Bioaccumulation

• School: University of Maryland
• Department: Maryland Institute for Applied Environmental Health
• Course: MIEH 300
• Professor: Devon Payne- Sturges

Document Summary

Name examples of consumer products that are sources of chemical exposures for humans. Identify federal agencies responsible for regulating chemicals fda, epa, usda. Identify challenges epa faces for regulating chemicals in consumer products under the toxic. Substances control act (tsca) (e. g. old vs new chemicals, potential overlap with other federal laws administered by other federal agencies) Explain factors epa considers in regulating chemicals under. Name 4 classes of pesticides and describe their toxic effects: organochlorines, blocks insect nervous system , causing death. Example is ddt, this causes cancer and impaired neurological function in humans: has potential to bioaccumulate up the food chain, organophosphates (op) Can cause hyper stimulation of muscles, uncoordinated, paralysis of insect, then death: carbamates. Inhibits the enzyme that breaks down neurotransmitter acetylcholine at the nerve synapse. Less toxic than op but closely related: pyrethrins. Paralyzes insects by interfering with neurotransmission of neural impulses via sodium channels. On clothes of workers/ take home exposures.