BY 108 Chapter Notes - Chapter 25: Cytotoxic T Cell, Natural Killer Cell, Humoral Immunity
Document Summary
Vaccination - infecting harmless virus in order to improve resistance. Antigen - molecule provoking a specific immune response. Antigenic determinant site - parts of antigen that stimulates an immune response. Created by b cells (made/mature in bone marrow) Secreted into body fluid >> humoral immunity. T cells (mature in thymus) directly attack the cells >> cell-mediated immunity. Exposed to pathogen, gaining immunity >> active immunity. Gaining antibodies from someone else >> passive immunity starting the immune response - mhc proteins on cell surface. Serves as cellular fingerprint >> body can distinguish between its cells + foreign cells >> self-versus-nonself recognition. Antigen-presenting cells - partially digests microbes, moves their antigens to the surface lets t cells recognize the antigens. Mhc-i - found on all body cells. Mhc-ii - found only on macrophages, b cells, and cd4+ t cells interleukin-1 - acts as chemical alarm signal between cells. Helper t-cell - detects infection, initiates b/t cell responses.
