BIO SCI 93 Chapter Notes - Chapter 17: Aminoacyl-Trna, Ribosomal Rna, Transfer Rna

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BIO SCI 93 Full Course Notes
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As a molecule of mrna is moved through a ribosome, codons are translated into amino acids, one by one. The interpreters are trna molecules, each type with a specific nucleotide triplet called an anticodon at one end and a corresponding amino acid at the other end. A trna adds its amino acid cargo to a growing polypeptide chain when the anticodon hydrogen bonds to the complementary codon on the mrna. Anticodon: one end of the trna; particular nucleotide triplet that base-pairs to a specific mrna codon. Enzymes called aminoacyl-trna synthetases carry out the correct matching up of trna and amino acid. Translation is initiated when mrna, trna bearing the first amino acid of the polypeptide, and the two subunits of a ribosome are gathered together. A large ribosomal subunit completes the initiation complex; proteins called initiation factors are required to bring all the translation components together.

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