BIO SCI 97 Chapter Notes -Dihybrid Cross, Phenylalanine, Phenylketonuria

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Incomplete dominance: heterozygotes have a phenotype intermediate to the two alleles. More than one phenotype at the same time. If you have a and b, then you will have both of the alleles and not just one that is dominant over the other. A and b are codominant of each other. The phenotype of both alleles is fully expressed in heterozygotes. Penetrance: the probability that a mutation will manifest its phenotype. Waardenburg syndrome dominant trait variable expressivity. Multiple symptoms only some manifest in each individual. Epistasis - two different gene loci that control the same trait. Epistasis occurs when there is phenotypic interaction of non-allelic genes: one gene can mask another. For epistatic genes, a dihybrid cross produces a modified 9:3:3:1 ratio of phenotypes. Genotypic ratios do not change, just the phenotypes produced. Genes alone are not responsible for all the variation seen between organisms.

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