LIFESCI 2 Chapter 43: Chapter 43 Notes

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30 Oct 2016
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Neural pathway: skin receptors sensory neuron interneuron motor neuron effector, extremely rapid response. Classification of muscles: muscles are contractile tissue, 3 types. Radial and circular muscles in the eye. Sarcomere: each myofibril is made of functional units of contraction called sarcomeres, each sarcomere is bound by a network of interconnecting proteins called z lines, thick filaments are composed of a contractile protein (myosin) Myosin is connected to the z line by the protein titin. Each myosin molecule is made of two heads and two tails: thin filaments contain a contractile protein (actin) and two regulatory proteins (troponin and tropomyosin) Globular protein that polymerizes to form intertwined helix. Actin has a binding site for myosin. Tropomyosin is the ribbon like protein that raps around the binding site. Made of three spherical subunits: actin binding site, tropomyosin binding site, calcium binding site.

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