LIFESCI 2 Chapter Notes - Chapter 6: Alpha Cell, Blood Sugar Regulation, Pepsin

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Metabolism: sum of chemical reactions in cells. Catabolic reactions: breakdown molecules/covalent bonds to release energy (e. g. cellular respiration); hydrolysis reactions. Anabolic reactions: formation of complex molecules using energy; condensation/dehydration reactions. Bioenergetics: flow of energy in biochemistry systems. Kinetic energy: energy associated with motion; generates heat. Potential energy: energy of state/position (stored energy in macromolecules) E. g. when jumping from somewhere high, potential energy converted to kinetic energy. 1st law of thermodynamics: energy can"t be created or destroyed; quantity of energy before & after the transformation is equal. Less energy of product than energy of reactants; the difference released. +ve g coupled with exergonic reaction; exergonic reaction generates energy which is used in endergonic reaction. The only thing enzyme alters is the kinetics (speed), doesn"t alter outcome ( g) Induced fit: enzyme changes shape a little to accommodate the substrate. Eventually after the reaction enzyme goes back to original shape -> recycled.

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