LIFESCI 4 Chapter Notes - Chapter 17.1: Reading Frame, Archibald Garrod, Neurospora Crassa
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17. 1 genes specify proteins via transcription and translation. Beadle and another scientist, tatum soon worked with a bread mold, neurospora crassa. They found strong support for the one gene - one enzyme hypothesis , which states that the function of a gene is to dictate the production of a specific enzyme. Getting from dna to protein requires two major stages: transcription: the synthesis of rna under the direction of dna. transcribe means copy. So dna provides a template for the assembling of a sequence of rna nucleotides. The resulting rna molecule, the messenger rna (mrna) is a transcript of the gene"s protein-building instructions. Dna to the protein-synthesizing machinery of the cell. Why can"t the proteins be simply translated directly from the dna: 1) provides protection for the dna and its genetic information, 2) using rna intermediate allows more copies of a protein to be made simultaneously.