LIFESCI 7B Chapter Notes - Chapter 3: Endergonic Reaction, Exergonic Reaction, Kinetic Energy

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Interpret graphs of free energy vs. progress of reaction to determine the thermodynamic favorability, likelihood of coupling, and relative rates of reactions for different chemical reactions. Types of energy: kinetic energy, energy from movement, potential energy, energy stored such as in concentration gradients, chemical energy, potential energy from bonds. Laws of thermodynamics: 1st law, conservation of energy, can neither be destroyed nor created only change form, 2nd law, entropy tends to increase. Reactions w increasing entropy is spontaneous because no heat is required. Coupled reactions: endergonic reactions can be coupled with exergonic ones, for example hydrolysis of atp releases energy which can be used to form bonds, enzymes coordinate these reactions, active site is shaped like substrates. Activation energy: the higher the activation energy needed, the slower the reaction, high concentration of reactant or product can affect which way a reversible reaction will go, enzymes can speed up reaction in both directions.

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