ESS 2 Chapter Notes - Chapter 4-5: Duloxetine, Aripiprazole, Psilocybin

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Agonist: a substance that facilitates or mimics the effects of a neurotransmitter on the postsynaptic cell. Antagonists: a substance that prevents the effects of a neurotransmitter on the postsynaptic cell. Monoamine: a class of chemicals characterized by a single amine group. Generic (not the chemical) names are the official names of drugs and are listed on usp. A name that specifies a particular chemical but not a particular brand. A variety of drugs prescribed by phyiscians for the control of mental problem. Group of analgesic (painkilling) drugs that produce a relaxed, dreamlike state. Relacat but doesn"t share most of the feature of that class. Therapeutic index (ti) is defined as (lethal dose for 50% of tested animal)/ (effective dose for 50% of tested animal) Safety margin: dosage difference between an acceptable level of effectiveness and the lowest toxic dose. Cumulative effects: effects of giving multiple doses of the same drug.

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