BILD 1 Chapter Notes - Chapter 17: Neurospora Crassa, Rna Splicing, Alternative Splicing
18 Dec 2018
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17. 1 genes specify proteins via transcription and translation. Dna inherited by organism leads to specific traits by dictating the synthesis of proteins and of rna molecules involved in protein synthesis. Gene expression: process by which dna directs synthesis of proteins. Genes dictate phenotypes through enzymes proteins that catalyze specific chemical reactions in cell. Cells synthesize and degrade most organic molecules via metabolic pathways. Disable one allele of protein coding gene required for specific metabolic activity. From minimal medium wild type mold cells use metabolic pathways to produce all other molecules they need for growth. Diff neurospora cells unable to synthesize particular essential nutrient cells could not grow on minimal medium must grow complete medium. Each nutritional mutant gene for enzyme that synthesize particular nutrient. One gene - one enzyme hypothesis: function of a gene is to dictate the production of a specific enzyme. Many proteins made from two or more diff polypeptide chains polypeptide is specified by own gene.
