BISC300 Chapter Notes - Chapter 16: Maclyn Mccarty, Replica Plating, Mutation

• School: University of Delaware
• Department: Biological Sciences
• Course: BISC300
• Professor: Cooper Carlton

Document Summary

This chapter begins with a discussion of mutation and genetic variation and includes molecular mechanisms of mutation and repair. A general discussion of bacterial recombination, plasmids, and transposable elements follows, with examination of the acquisition of genetic information by conjugation, transformation, and transduction. After studying dr. cooper"s power point with animations and the links provided here, you should be able to: Discuss the two causes of mutations and what are the effects of mutations (see table 16. 2) Including point mutations, transition mutations, transversion mutations, etc. Auxotroph vs prototroph (figure 16. 6 and 16. 7) Describe replica plating and explain how it used to identify mutant phenotypes (or auxotrophs) Distinguish horizontal gene transfer (hgt) from vertical gene transfer (vgt) Compare and contrast conjugation, transformation, and transduction (generalized and specialized transduction) and lytic and lysogenic cycles (of transduction) Who was fred griffith and what was his experiment in 1928? http://www. ncbi. nlm. nih. gov/books/nbk22104/ How did oswald avery, colin mcleod, and maclyn mccarty improve dr. griffith"s experiment? http://www. dnaftb. org/17/animation. html.