7. 1 most bacteria and archaea reproduce by binary fission: eukaryotic microbes differ dramatically from bacteria and archaea in their reproductive strategies. Many eukaryotic microbes exhibit both asexual reproduction, involving mitosis and sexual reproduction, involving meiosis to produce gametes or gamete like cells. Eukaryotic microbes often alternate bw. haploid and diploid stages in their life cycles: most bacterial and archaeal cells reproduce by binary fission. The cell elongates as new material is synthesized, replicates its chromosome, and separates the newly formed dna molecules so there is one chromosome in each half of the cell. Finally, a septum (cross wall) is formed at midcell, dividing the parent cell into 2 progeny cells, each having its own chromosome and a complement of other cellular constituents: some bacteria reproduce by forming a bud. Other bacteria form mutlinucleoid filaments that eventually divide to form uninucleoid spores: despite the diversity of bacterial reproductive strategies, they share certain features.