BSC 2010 Chapter Notes - Chapter 3: Competitive Inhibition, Organic Compound, Allosteric Regulation
26 Apr 2017
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A and t have double bond (hydrogen), while c and g have triple bond though many hydrogen bonds make force of attraction strong, modest input of energy (covalent bonds) can break base pairs. No catalyst makes a reaction occur that would not proceed without it. Enzyme lowers energy of activation by allowing reactants to react more easily. Substrates are reactants in enzyme catalyzed reactions, substrate converted to products that are then released free enzyme may change chemically in reaction, but goes back. Enzymes induce strain (cause substrate to stretch and make unstable transition state) Substrate orientation (when free, vibrate and move, orient to react) Add chemical groups (r groups can be involved in reaction) Coenzyme binds to active site of enzyme, adds/removes chemical group from substrate, separates to go to another reaction. Prosthetic group= organic molecule permanently bound to enzyme. Higher concentration of substrate, faster rate; concentration of enzyme usually lower than substrate.
