BSC 2011 Chapter Notes - Chapter 43: Natural Killer Cell, Antigen-Presenting Cell, B Cell

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Mucous membranes that cover epithelial linings and surfaces: physical barrier as well. Secretions that lower skin ph: lysozymes: digests bacterial cell walls, cellular innate defenses, phagocytic white blood cells (wbc) or leukocytes, neutrophils: leukocytes that ingest + destroy microbes (phagocytosis) Most abundant leukocyte: eosinophils: leukocytes that discharge hydrolytic enzymes when in close proximity to parasites (eukaryotic organisms, monocytes: phagocytic leukocytes that develop into macrophages. Stimulate other immune responses: antimicrobial proteins, interferon: innate defense against viral infections. Alter cells adjacent to viral-infected cells to produce substances that inhibit viral replication: complement system: leads to the lysis of invading cells, inflammatory response. Tissue damage due to physical injury (trauma) or pathogen entry. This triggers the release of chemical signals which result in an inflammatory response: histamine chemical released in response to injury. Delivers clotting agents & phagocytic cells to the injured area. Trigger the dilation and permeability of nearby capillaries. Stored in mast cells (mastocyte) (found in connective tissues)

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