BCMB 3100 Chapter Notes - Chapter 2 & 3: Ionic Bonding, Hydrogen Bond, Weak Interaction

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Proteins, nucleic acids, lipids, & carbohydrates are very stable because of their strong covalent bonds (bonds that share electrons) that make them up. However, things that make up these biomolecules are stabilized by weak interactions, many weak bonds can result in large stable structures: weak bonds allow dynamic interactions. If a molecule is hydrophobic, it is also nonpolar. Cell and organelle membranes form because of the hydrophobic effect. Ionic bonds aka electrostatic interactions/salt bridges: interactions between distinct electrical charges on atoms, water weakens ionic bonds, example: nacl; when nacl (salt) is added to water, the salt dissolves aka the ionic bond between na & cl dissolved. This bond then reforms with water: full, permanent changes, hydrogen bonds: an attractive (dipole-dipole) interaction b/w an electronegative atom & H atom bonded to another electronegative atom: hydrogen bonds are much weaker than covalent bonds, water can disrupt hydrogen bonding.

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