IB 150 Chapter Notes - Chapter 12,13,14,16: Missense Mutation, Frameshift Mutation, Sister Chromatids

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Genetic screen - technique for picking particular types of mutants out of many randomly generated mutants. Mrna - carry info out of nucleus from dna to site of protein synthesis. Rna polymerase - polymerizes ribonucleotides into strands of rna. Uses strands of dna as template to determine complementary nucleotide to add to growing strand. Central dogma - summarizes flow of information in cells. Transcription - process of using dna template to make an rna molecule that has base sequence complementary to dna. Dna = transcribed to rna by rna polymerase. Translation - process of using info in mrna to synthesize proteins. Info stored in mrna is translated to proteins by ribosomes. Dna transcription mrna translation proteins. Dna rna proteins phenotype. Info sometimes flows from rna back to dna. Reverse transcriptase - viral enzyme that synthesizes dna version of rna genes. Mutation - permanent change in organism"s dna.

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