BIOS 111 Chapter Notes - Chapter 14: Benzathine Benzylpenicillin, Citric Acid Cycle, Adenine
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Produces lipoproteins to stimulate inflammatory response: causes tissue destruction. Mutated into an std with european explorers: relatively rare in affluent societies, primary stage syphilis. Appears on infected site 10-90 days following exposure. Bacteria enter bloodstream and lymphatic system: secondary stage syphilis. Loss of patches of hair, malaise, mild fever. Lesions of rash contain highly contagious spirochetes. Unlikely to get it off of environmental surfaces: latent period. Not infectious except from mother to fetus: tertiary stage syphilis. Classified by affected tissues or type of lesion. Gummas forms of progressive inflammation that appear as rubbery masses of tissue in various organs: cause local destruction of tissues, not death. Common when pregnancy occurs in latent period of disease. Pregnancy during primary or secondary stage will likely produce stillbirth: diagnosis of syphilis. Do(cid:374)"t detect a(cid:374)tibodies produced against spirochete: detect regain-type antibodies. Antigen used is extract of beef heart. Rapid diagnostic tests (rdts: finger prick blood sample.
