NSC-2201 Chapter Notes - Chapter 15: Reward System, Sympathomimetic Drug, Striatum

• School: Vanderbilt University
• Department: Neuroscience
• Course: NSC-2201
• Professor: Smith

Document Summary

Ch 15: chemical control of the brain and behavior. > stimulate release of peptide called corticotropin-releasing hormone (crh) into blood of portal circulation > 15 sec later it stimulates release of corticotropin or adrenocorticotropic hormone (acth) > Preganglionic axons emerge from middle third of spinal cord (thoracic and lumbar segments) Preganglionic neurons lie within intermediolateral gray matter of spinal cord. Preganglionic neurons send axons through ventral roots to synapse on neurons in ganglia of sympathetic chain, next to spinal cord. Preganglionic axons emerge from brainstem and sacral segments. Preganglionic neurons axons travel within several cranial nerves and nerves of sacral spinal cord. Local effect, acts entirely through machr spreads far, even into blood to circulate. Parasympathomimetic drugs promote muscarinic actions of ach or inhibit actions of ne more. Sympathomimetic drugs promote actions of ne or inhibit muscarinic actions of ach: adrenaline released from adrenal medulla so adrenal medulla is really like a modified sympathetic ganglion, epinephrine made from norepinephrine.