NURS 324 Chapter Notes - Chapter 3: Deep Vein Thrombosis, Lymph Node, Collagen

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* formation and development of blood and blood cells. * key components (table on p 52 blood cells and their function) * erythrocytes- most prevalent cell type in the body. * thrombocytes- platelets; thrombocytes, along with clotting factors, control coagulation. Coated with a sticky material that causes them to adhere to irregular surfaces. * a chain reaction begins almost instantly after damaged the endothelial lining of a vessel. Clotting cascade (don"t need to know all the clotting factors) * tissue injury leads to the release of tissue factor. * through a series of steps thrombin is generated and released. * ultimately leads to thrombus formation. i. ii. Factor xa and va then form a complex which activates prothrombin and converts to thrombin iii. * normal range = 5,000 to 10,000 mm3. * leukocytosis- too many leukocytes in the blood (could be an indicator of infection) * leukocytopenia- too little leukocytes in the blood (immune deficiency state)

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