BIOL126 Lecture Notes - Lecture 6: Choroid Plexus, Dura Mater, Pia Mater

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Protection in the Nervous System
3.23. The location and function of ventricular system of the central nervous system
-Protection and Support
-Meninges stabilize brain in cranial cavity
-Cerebrospinal fluid protects against sudden movement
-CSF provides nutrients and removes wastes
-Blood–brain barrier and blood–CSF barrier
-Selectively isolate brain from chemicals in blood that might disrupt neural function
3.24. The cerebrospinal fluid (CSF)
3.24.1. its roles in protecting and nourishing the brain
-Cushions delicate neural structures
-Supports brain
-Transports nutrients, chemical messengers, and waste products
-Produced by the choroid plexi of the ventricles
3.24.2. where it is made and how production and reabsorption are balanced
3.24.3. its circulation through the ventricles and subarachnoid space
3.25. The location of the meninges
3.25.1. dura mater
-"hard mother"
-thick, tough, inelastic
-2 layered meningeal & periosteal
-Outer dura (periosteal) attaches to inner skull
-Inner dura (meningeal) attaches to arachnoid
-Spinal dura (1 layer only) attaches to coccyx (filium terminale externum)
3.25.2. arachnoid mater
-thin cell layer with arachnoid trabeculae-- web-like collagen projections–to pia layer
-subarachnoid space containing CSF
3.25.3. pia mater
-thin, delicate, tightly covers all external contours;
-highly vascular - vessels lie on outer pia surface
3.26. Their role in protection of the brain and spinal cord
3.27. Features and role of blood-brain barrier:
-The blood-brain barrier isolates neural tissue from general circulation
-BBB arises due to the extensive tight junction interconnections between endothelial cells that
line the capillaries of CNS
-Also, processes of astrocytes completely cover outer endothelial surface of capillaries in CNS
-Astrocytes also regulate permeability of the endothelium by releasing chemicals
-Maintains a constant environment for the neural tissue
3.27.1. blood-CSF barrier
-Ependymal cells are connected by tight junctions, surrounds the capillaries of choroid plexus
-Choroid plexus (which produce CSF) filter blood and let some substances in but not others
3.27.2. vascular-endothelial barrier
- ‘Tight junctions’ between adjacent endothelial cells of brain capillaries
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3.27.3. arachnoid barrier
-Arachnoid provides an additional barrier between dural vessels and subarachnoid space
Peripheral Nervous System
3.28. The Peripheral Nervous System (PNS)
3.28.1. the two major pathways -sensory and motor
3.28.2. the somatic and autonomic systems
-Somatic (Voluntary)
-Spinal Nerves
-Cranial Nerves
-Conveys information from the periphery. It is in effect a collective description for all sensations
-The output of the somatic nervous system is exclusively to skeletal muscle
-Thus the output of the somatic nervous system results in movement
-Autonomic (Involuntary)
-Sympathetic
-Parasympathetic
3.29. Protection of spinal nerves
Protected by meninges and vertebrae.
3.30. The cranial nerves
3.30.1. the names and main functions of the twelve cranial nerves
3.30.2. the course (including the passageway taken to exit the skull) of each nerve
3.30.3. where each cranial, nerve attaches to the brainstem
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Document Summary

The location and function of ventricular system of the central nervous system. Selectively isolate brain from chemicals in blood that might disrupt neural function. 3. 24. 1. its roles in protecting and nourishing the brain. Transports nutrients, chemical messengers, and waste products. Produced by the choroid plexi of the ventricles. 3. 24. 2. where it is made and how production and reabsorption are balanced. 3. 24. 3. its circulation through the ventricles and subarachnoid space. Outer dura (periosteal) attaches to inner skull. Spinal dura (1 layer only) attaches to coccyx ( lium terminale externum) Thin cell layer with arachnoid trabeculae-- web-like collagen projections to pia layer. Thin, delicate, tightly covers all external contours; Highly vascular - vessels lie on outer pia surface. Their role in protection of the brain and spinal cord. The blood-brain barrier isolates neural tissue from general circulation. Bbb arises due to the extensive tight junction interconnections between endothelial cells that line the capillaries of cns.

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