NEUR30002 Lecture Notes - Lecture 35: Electric Field, Extracellular Fluid, Spatial Memory
11 Aug 2018
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It must mean that the whole dendrite is depolarised which means that another biological truism is about to bite the dust. * in the nervous system one of the great truisms is that axons are active and dendrites are passive. * the back propagation is due to voltage activated calcium channels in the dendrite and there are also a few voltage activated sodium channels (they are not as good as axons but they do have some propagating abilities). * note: most of the entorhinal cortex perforant pathway synapses on the dg neurons, but some goes straight to the ca3 and a relatively small number goes straight to ca1 they are all associative. * the perforant pathway is an example of associative ltp. So, it is information going from the entorhinal cortex to the dentate gyrus. *the mossy fibre pathway from the dentate gyrus to the ca3 pyramidal neuron is a non- associative ltp.
