BIOL 461 Lecture Notes - Lecture 5: Zygosity, Instar, Chromosome

• School: Concordia University
• Department: Biology
• Course: BIOL 461
• Professor: William Zerges

Document Summary

Discovery screen a mutant screen to identify those genes and gene products that are involved in establishing body pattern of complex multicellular animal & how that early pattern is established. Want to find the functions involved in establishing a pattern of an animal in embryonic development. Focus on skin of first instar larva because it has a beautiful stereotypic (reproducible) pattern easy to identify mutants that are altered in the pattern. Did mutant screen looking through mutagenized chromosomes for those genes that generate a phenotype that specifically are affected that pattern. Once you get a mutant with a phenotype you can work back to the function. What (cid:455)ou (cid:374)eed if (cid:455)ou"(cid:396)e doi(cid:374)g a (cid:373)uta(cid:374)t s(cid:272)(cid:396)ee(cid:374): (cid:455)ou (cid:272)a(cid:374)"t just get a (cid:373)uta(cid:374)t a(cid:374)d see the phe(cid:374)ot(cid:455)pe a(cid:374)d the(cid:374) th(cid:396)o(cid:449) it a(cid:449)a(cid:455). You (cid:374)eed to ha(cid:448)e a li(cid:374)e that"s generating those mutants.