BIOL 462 Lecture 1: BIOL 462 IMMUNOLOGY Lecture 1 notes
18 Feb 2019
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Document Summary
Immunity is the state of protection against foreign pathogens or substances (antigens) Physical (epithelial, stratum corneum) chemical (mucus, enzymes, enzymes) Humoral vs cell mediated responses: humoral everything which is soluble, cell mediated is everything that involves cells. Vaccination prepares the immune system to eradicate an infectious agent before it causes disease. 4 tasks of the immune system: immunological recognition, immune effector functions, immune regulation, immunological memory innate immunity. Innate immune responses fast, nonspecific first line of defence. Germline-encoded recognition molecules (part of our dna, combinatorial diversity is not there) Players: epithelial barriers, phagocytes, dendritic cells, plasma proteins, nk cells adaptive immune responses slower to develop (5-6 days + days) consists of humoral and cell mediated responses. Players: b cells antibodies, t cells effector t cells. The secreted antibody binds to foreign proteins or infectious agents, helping to clear them from the body.
