HTHSCI 2H03 Lecture Notes - Lecture 18: Reverse Cholesterol Transport, Coronary Artery Disease, Very Low-Density Lipoprotein

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 2H03
• Professor: kirsten

Document Summary

Triglycerides: account for 90% of total lipids in the body. Important source of energy (fuel in times of energy need) Phospholipids: essential for the formation of plasma membranes. Steroids: cholesterol, essential component of plasma membranes, building block for bile acids, vitamin d, cortisol, estrogen & testosterone. Liver can synthesize cholesterol; no need for source from diet. Lipids are not soluble in plas(cid:373)a a(cid:374)d (cid:396)e(cid:395)ui(cid:396)e (cid:862)spe(cid:272)ial pa(cid:272)kagi(cid:374)g(cid:863) to (cid:271)e dist(cid:396)i(cid:271)uted to (cid:271)ody tissues: complex of triglycerides, cholesterol and phospholipids with a protein carrier (apoprotein) 3 types of lipoprotiens characterized by composition, size and density: high-density lipoprotein (hdl) Low-density lipoprotein (ldl: very low-density lipoprotein (vldl) Ldl- low density lipoproteins: transports cholesterol from the liver to tissues; used to create plasma membranes and other steroids, cholesterol can be stored for later use. Vldl: primary carrier of triglycerides, converted into ldl; reduced to ldl.