MEDRADSC 3C03 Lecture Notes - Lecture 3: Microbubbles, Gadolinium, Iodine

• School: McMaster University
• Department: Medical Radiation Sciences
• Course: MEDRADSC 3C03
• Professor: Meaghan Jefferson

Document Summary

Increase visibility: regions of low subject contrast, administration will affect properties of tissues concerned, x-ray: affects tissue attenuation, ultrasound: tissue and blood reflectivity, mri: tissue relaxation time, need lot number and amount administered recorded for any potential reactions. Iodinated: high atomic number gives better contrast between media and other various tissues found in the body: non-iodinated, co2: considered negative contrast medium, lower attenuation compared to tissues. Us: fluorocarbon microbubbles: powder + saline before administration, sonorx: ingested, decreases bloating in patients decreases artifacts made by gas. X-ray contrast agents: binding compound used accounts for difference in contrast types. Ionic compounds have high osmolar concentration: highly soluble and low viscosity, non-ionic has lower osmolality decreasing risk of reactions, higher viscosity and more money. High osmotic agents: draw water and fluid from extravascular space to equalize pressure between membrane. Direct: secondary tot eh osmolality and direct to the chemotoxicity of the contrast. Includes: heat, nausea and pain: effects the organ system.