BIOL 102 Lecture Notes - Lecture 9: Molecular Machine, Proteome, Eukaryote
Document Summary
Rna and protein, genome and proteome: genome: an organism"s complete collection of dna, transcription: constructed by transcription, individual genes are copied into rna molecules, proteome: translation of these rna molecules into protein. Structure determines function: amino acid sequence produce certain types of folding (protein interlocking, subunits: self-assembly based on shape, shape allows for specific conformational changes to occur based on molecular recognition (inhibitors, enzymes) Example of a molecular machine: ribosomes, protein synthesis, cytoskeleton. Describe how a eukaryotic cell can be viewed as 4 interacting systems: nucleus: Organization + protection of chromosomes (near nuclear matrix: cytosol: Organization + movement via the cytoskeleton and motor proteins: semi-autonomous organelles: Mitochondria: atp snythesis, modification of organic molecules, heat production. Post-translational: sorting to nucleus, mirochondria, chloroplasts and peroxisomes (some) occure after the protein is made.