MBB 321 Lecture Notes - Lecture 7: Fructose, Isomerization, Isomerase

• School: Simon Fraser University
• Department: Molec Biol & Biochem
• Course: MBB 321
• Professor: Ingrid Northwood

Document Summary

Once glucose has entered the cell it is phosphorylated, and therefore it cannot rebind to the glucose transporter and. The enzyme glucose 6 - phosphatase, which is found in the kidney and liver, is a transporter that will remove the. Phosphate on the glucose so that it can be released into the bloodstream by a glucose transporter. The normal concentration of glucose in the bloodstream is 4 - 5 mmol. An increase in glucose in the bloodstream stimulates the secretion of insulin by the pancreas, which binds to the. This insulin stimulates glut4 and thus increases the rate of glucose uptake into muscle and adipose tissues when. As a result glucose levels decrease, which slows down the secretion of insulin and thus decreases the amount of. ) values indicate that the transporter has a high affinity for glucose at low concentrations which is. ) values indicate that the transporter has a low affinity for glucose at low concentrations which is.