Biology 1001A Lecture Notes - Lecture 6: Pyrimidine Dimer, Dna Repair, Atomic Orbital
24 Nov 2017
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Cell cycle checkpoints, cytoskeleton, complementary base pairing (telomerase) semi conservative replication helps ensure inheritance of sameness. Dna polymerase is not perfect sometimes it inserts the wrong base. Mutation is a double stranded change in the dna sequence; anything else is known as a damage. Many organisms can use the enzyme photolyase to repair the damage, enzyme binds to the dimer, break the covalent bonds, puts the thymine back the way they were, photolyase uses white light as energy. Sometimes repair enzymes make mutations trying to fix the strand. Mammals don"t have photolyase (cid:523)we lost it(cid:524). (umans don"t have the biggest set of genomes. Genome )s not a book it"s a dynamic ecosystem. We use excision repair to repair our cells. Fixing chromosomes is sloppy and can result in mutations. Inheritance of difference our genome is human genes. 25% of our genome is unknown jelly. Most of the genome is not coding for genes.
