Microbiology and Immunology 2500A/B Lecture Notes - Lecture 9: Polio Vaccine, Opportunistic Infection, Edward Jenner
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15 Jan 2017
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A modified form of an antigen given so that the host can generate b and t cell memory, which can act at a future day against the natural pathogen. Someone who have not have had a vaccine or been exposed to the pathogen, will not develop memory b and t cells. They get very sick when exposed to the pathogen. Vaccines can protect people that have had the vaccine, but more importantly it protects the people in the population that can"t get vaccines. Break/block in transmission cycle in the population. Vaccinated people can"t be infected, thus no transmission of the pathogen. However, this depends on the immunity within the population. Must reach a threshold of people vaccinated (% of vaccinated people) Most pathogens in our populations have reached the threshold. However, if the immunity levels in the population drops the whole population becomes significantly more susceptible. Mmr controversy caused a decrease in vaccinations rates, thus an increase in infections.
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