Pathology 3245B Lecture 1: Diseases of Urinary Tract and Kidney - Armstrong
12 Jan 2017
School
Department
Course
Professor
Document Summary
Diseases of urinary tract & kidney - armstrong. Elimination of toxins, drugs, metabolic waste: maintains electrolytes (salt balance), water balance, blood ph. Regulate vitamin d activity by activating vitamin d (essential for formation of bones & balance of calcium) Note: kidney does not make vitamin d, only activates it. Stimulate rbc production at the bone marrow (erythropoietin) 25% of cardiac output is at the kidneys. Kidneys maintain homeostasis & regulation in addition to filtering fluids. Concentration occurs in the medulla of the kidney. Renal pyramids dump out fully processed urine to the renal pelvis urinary tract. Glomerulus = functional filtration unit; spaghetti coils of capillaries. Coils of (cid:272)apillaries are surrou(cid:374)ded (cid:271)(cid:455) a (cid:272)apsule of epitheliu(cid:373) (cid:894)bo(cid:449)(cid:373)a(cid:374)"s capsule), which collect filtrate. Podocytes cells which have little projections/feet and wrap around the capillaries while forming little slits in-between (called slit processes) Lining of endothelium is fenestrated (part of the filter)
