CAS PS 101 Lecture Notes - Lecture 8: Amyloid Beta, Temporal Lobe, Long-Term Memory
17 Oct 2018
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Document Summary
Brain scan of normal brain vs alzheimer"s brain. Symptom of alzheimer"s: issues with language )(finding the right words, large section of temporal lobe missing- long term memory of how words sound stored here) Increase in ventricles that hold tissue so brain does not get crushed. Areas of brain tissue: shrunken hippocampus (lost memory formation and gps, shrunken cortex (lost problem solving (cognition), strategy, attention) Chemical neurotransmitters: acetylcholine (lost memory, gps, problem solving, strategy, norepinephrine (lost attention) What"s added in the alzheimer"s brain: increased amyloid protein (unhealthy in excessive amounts) and tau, increased plaques and tangles. 50% of americans over 85 have alzheimer"s disease. Controversial if african americans/ hispanics are more susceptible. Age of patient (not dementia if closer to 60 or younger) Perform a drawing test of 2 overlapping 2d shapes. Block enzymes designed to clean up acetylcholine (only saves what"s left) At risk for alzheimer"s + unknown environmental factors = cause alzheimer"s.
