NUR 424 Lecture Notes - Lecture 6: Abdominal Compartment Syndrome, Pulse Pressure, Shortness Of Breath
Document Summary
Overview of shock: adequate blood flow: cardiac pump; circulatory system; blood volume, shock perfusion to cells inadequate, decrease o2, decreased nutrients to support cellular function, vital organs, responses: hypoperfusion of tissues, hypermetabolism, inflammatory response. Hypermetabolic because the body is trying to compensate for the loss of nutrients and energy. Inflammatory response because there is some kind of assult on the body. Normal physiology: nutrients broken down, stored as adenosine triphosphate (atp0, atp used/needed for cellular functions, atp synthesis aerobic or anaerobically, anerobically synthesis -> increased lactic acid. Chemicals released -> hyperglycemia and insulin resistance. Gluconeogenesis to meet energy needs: cellular metabolism impaired, cellular effects of shock. Vacular and blood pressure: vasodilation or vasoconstriction in response to biochemical mediators, circulatory system. Mean arterial bp = co x peripheral resistance. Map must be > 65mmhg ( if not poor perfusion) Physiologic response to decrease bp: catecholamines, chemoreceptors, renin-angiotensin, aldosterone -> increased na and increased h2o -> adh -> increased h20.
