01:694:301 Lecture Notes - Lecture 4: Dna Replication, Nucleic Acid Double Helix, Intron
14 Nov 2018
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Document Summary
Replication dna synthesis; dna forms double helix: each strand of helix serves as template for another dna replication. Transcription dna is not the direct template for protein synthesis. Dna is copied into rna (mrna specifically), the info carried intermediates in protein synthesis. A sequence of 3 bases codon specifies an amino acid. Mosaic of nucleic acid sequences introns and exons (both transcribed) Introns are cut out to newly synthesized rna molecules, leaving mature. Rna with continuous exons: as with proteins in order to understand the polymer, we have to look at the monomer, here the monomer are nucleotides, each nucleotide has a base", a sugar, and a phosphate. Both sugar and phosphate make up backbone" of dna: sugar in dna is deoxyribose, lack 2" hydroxyl group, phosphates form phosphodiester bridges (negative charge less susceptible to hydrolytic attack resistant, refer pg.
