BSC 114 Lecture Notes - Lecture 4: Francis Crick, Globular Protein, The Sequence

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The structure and function of large biological molecules: Within cells, small organic molecules are often joined together to form larger molecules, called macromolecules o. All living organisms are made up of four classes of macromolecules. A polymer is a long molecule consisting of many similar building blocks called monomers o. Two of the four classes of life"s macromolecules consist of only polymers: proteins and nucleic acids o. A third class, carbohydrates, consists of monomers, dimers, and polymers. In biological systems, monomers form larger [bio]polymers by dehydration reactions- covalent bonding of two molecules to each other through loss of a water molecule o hydrogen o. One molecule provides a hydroxyl group (-oh) and the other provides a. To make a polymer, the dehydration reaction is repeated as monomers are added one by one. Biopolymers are disassembled to monomers by hydrolysis- the reverse of dehydration synthesis o o. Bonds are broken by the addition of water molecules.

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