BSC 300 Lecture Notes - Lecture 9: Acetyl-Coa, Cellular Respiration, Mitochondrion

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Bsc 300 lecture 9- aerobic respiration and the mitochondrion. Early earth was populated by anaerobes, which captured and utilized energy by oxygen- independent metabolism. Oxygen accumulated in the primitive atmosphere after cyanobacteria appeared. Aerobes evolved to use oxygen to extract more energy from organic molecules. In eukaryotes, aerobic respiration takes place in the mitochondrion. Typical mitochondria are bean-shaped organelles but may be round or threadlike. Size and number of mitochondria reflect the energy requirements of the cell. Diverse cellular roles in addition to energy production: Mitochondria can fuse w/ one another, or split in two. The balance between fusion and fission is likely a major determinant of mitochondrial number, length, and degree of interconnection. Inner and outer mitochondrial membranes enclose two spaces: the matrix and intermembrane space. The outer mitochondrial membrane serves as its outer boundary. The inner mitochondrial membrane is subdivided into two interconnected domains: Cristae- where the machinery for atp is located.

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