BSCI 105 Lecture Notes - Lecture 5: Flavin Mononucleotide, Isocitric Acid, Organic Compound
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Etc pathologies, fermentation and alternate substrates (note: if we have time on monday 3/28 we will cover regulation if not, we won"t and you are not responsible for it. ) Causes the h+ to flow back into matrix. No gradient is established, so no atp is. Antimycin: antibiotic, blocks movement of electrons from cyt b, it can be reduced but not oxidized. Cyanide: will impact on all of the cytochromes but biggest impact is at cytochrome oxidase (iv). Binds to atp synthase in a way to block the proton channel. It has no impact on electron transport or the proton gradient. Many prokaryotes use alternative final electron acceptors: methanogens. Co2 is reduced to ch4: sulfur bacteria. If cell needs energy goes into krebs cycle. If cell doesn"t need energy converted into glucose, then glycogen. If cell doesn"t use oxygen goes into fermentation. Glycolysis is nad+ limited and stops (cell dies very bad) The purpose of fermentation is to recycle nad+