BIOL 2081C Lecture Notes - Lecture 9: Hypoesthesia, Brca2, Zygosity
Document Summary
We are continuing our discussion of dna inheritance, by examining pedigrees, which are visual representations of the phenotypes of an entire family. Geneticists use pedigrees to make predictions about the mode of inheritance of a certain phenotype. Pedigree analysis is also the way that geneticists and genetic counselors determine the odds that a couple may conceive a child with a genetic condition. Reading assignment: hartl, section 3. 5 (no need to read the section on baye"s theorom). 11), mitochondrial and cytoplasmic (lecture 30) modes of inheritance. Mutants/diseases could be dominant, if seen frequently in the pedigree. If not seen frequently, it would be considered recessive: calculate the probability that an individual in a pedigree has a particular genotype, including conditional probability as explained in problem 1" on p 101. Download and read (not the whole thing, use the prompts below to guide your reading): Kif1a, an axonal transporter of synaptic vesicles, is mutated in hereditary sensory and autonomic neuropathy type 2.
