PSYC 181 Lecture Notes - Lecture 11: Coca, Vin Mariani, Sodium Bicarbonate
Document Summary
Opium was unreliable; cocaine found with local anesthetic effects, so replaced opium: cocaine is a stimulant; great for surgery because stimulants stop blood flow, so stop bleeding during surgery, cocaine replaced by other drugs: procaine, etc. Cocaine history of use: used in coca cola, vin mariani, cocarettes: cigarettes with cocaine in them. What america spends on drugs: mostly cocaine and heroin, marijua(cid:374)a is (cid:271)ig, (cid:271)ut do(cid:374)"t profit a lot from it. Not stable unless turns into a salt: cocaine hcl. Snorted or iv: cocaine free base. Smoked: crack (called crack because it crackles when you burn it) Free base made with baking soda and ammonia, not cheaper. Effects of cocaine: very similar to amphetamine (generalize in drug discrimination), but some major differences: Work by blocking voltage gated na+ channels. Cocaine makes up most drug er visits: restri(cid:272)ts (cid:271)lood flow, si(cid:374)(cid:272)e it"s a sti(cid:373)ula(cid:374)t.
