MCB 300 Lecture Notes - Lecture 28: Natural Killer Cell, Innate Immune System, Lactoperoxidase

• School: University of Illinois
• Department: Molecular and Cell Biology
• Course: MCB 300
• Professor: C Vanderpool

Document Summary

Mcb 300 lecture 28: pathogenic microbe-host interactions-ii: host barriers to microbial. - infectious diseases are a major source of world-wide morbidity and mortality. - new infectious diseases will continue to emerge and old diseases will continue to reemerge in a manner that reflects changes in the environment (including human behaviors!!) - the capacity of a microorganism to potentially cause disease is dependent on pathogen acquisition of virulence factors. - host susceptibility to pathogens depends on a variety of factors, including age, underlying health issues, nutritional status, stress, antibiotic usage, injury/ surgery, exposure, vaccination status, and genetic differences between hosts. The changing view of what is means to be human . Premise: although microbial-host interactions are largely neutral or beneficial, this is in part because the host can successfully limit access of microbes to specific niches in the body . - human physiology is largely influenced by the microbes that inhabit our bodies.