MCB 300 Lecture Notes - Lecture 27: Gastrointestinal Tract, Human Microbiota, Microbiota
Document Summary
Mcb lecture 27 pathogenic microbe-host interactions-i: introduction to infectious diseases and. - the diversity and changing properties of the human gastrointestinal tract as one moves from the. Stomach to the rectum is reflected in the diversity and changing properties of the gut microbiota. - the gut microbiota is established early in life, and the highly dynamic nature of the microbiota have profound effects on human physiology! - microorganisms in the gut have the genetic potential to provide metabolic capacities that we do not have. - the gut microbiota provides metabolic potential !hat influences the synthesis and storage of fatty acids. - microorganisms in the infant gut all change over time in a similar manner to become increasingly like the adult gut microbiome. - the human microbiome can be manipulated using strategies to exclude pathogenic bacteria. - one strategy for manipulating the human microbiota to promote human health is to introduce species that have natural antimicrobial activity against pathogenic bacteria.