BIOS 230 Lecture Notes - Lecture 4: Point Mutation, Purine, Hbb

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30 Jan 2017
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Small changes over 100"s of thousands of years can create huge changes in evolutionary time. Translation of darwin"s principles into precise genetic terms. Microevolution: allele frequency changes over relatively short time spans. Gene frequencies are characteristics of populations, not individuals. Population: a group of organisms of the same species among whom mating occurs. Gene pool: the total genetic makeup of all members of a population. Mutation: a heritable change in genetic material (dna) There are only four things that can change allele frequencies: mutation, genetic drift, gene flow (migration, natural selection. Genes are stretches of dna that code for a distinct rna or protein product. Alleles are versions of the same gene that differ in sequence. If a genetic locus has 3 alleles how many possible genotypes are there = 6 or 3! A and g are purines and c and t are pyrimidines. Purines to purine or pyrimidine to pyrimidine is called transitions.

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