MCDB 427 Lecture Notes - Lecture 13: Plasmid, Adventitiousness, Restriction Enzyme
21 Dec 2016
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We have been focusing on how rnap)) and it"s buddies get on the promoter regions. Now we"ll be talking about the nucleosomes that are present on the dna (cid:523)purple with the help of activator proteins. They are bimodal proteins and can interact with different subunits of the transcription activators. There are other factors than gtfs that are involved in transcription events images) To prevent this, we can modify them with multi-protein complexes that change the modification state of the protein or we nudge them out of the way or change their conformation. They are small and very conserved, bind to dna. You need a lot of histones in the cell. There are 2 of each of these proteins which the dna wraps around about 1. 7 times run like regular proteins. They have n and c terminal extensions (which will become important later)
